Il laboratorio di Chimica e Biochimica delle Proteine (stanza n. 231) è situato al primo piano del cosidetto “vecchio edificio di Agraria”.
Principali linee di ricerca:
1. Miglioramento delle qualità nutrizionali e di difesa di piante di interesse agronomico
– isolamento e caratterizzazione (chimica, biochimica e chimico-fisica) di proteine vegetali di interesse agronomico
– espressione eterologa (in batteri, lieviti, piante) di inibitori proteici di proteinasi
– tecniche di mutagenesi sito-specifica per la produzione di forme mutate di proteine di interesse agronomico
2. Produzione di proteine vegetali chimeriche caratterizzate da attività citotossica selettiva nei confronti di cellule tumorali
– progettazione di costrutti genici chimerici
– espressione eterologa di proteine chimeriche
– tecniche di “protein refolding”
– caratterizzazione citotossica di proteine chimeriche
3. Studio delle relazioni tra livelli enzimatici endogeni e composizione in composti fenolici nel frutto e nell’olio vergine di oliva
Collaborazioni in atto:
Responsabile: Professore Ordinario Elia Poerio
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